|Research area||Unravelling the fundamentals of glucocorticoid actions across vertebrates|
|Research topic||Chronic stress, target glucocorticoid receptor profiles and ligand binding kinetics|
|Species||Carp (Cyprinus carpio)|
This study focuses on the influence of maternally deposited and early life (stress induced) de novo synthesis of glucocorticoids by the Hypothalamic-Pituitary-Interrenal axis using carp (Cyprinus carpio) as a model: the effect of cortisol and its endogenous phase I metabolites on glucocorticoid (pre-)receptor regulation in brain and bone.
Keywords: fish, HPI, glucocorticoid, stress, bone
Ghent University, Belgium (Aerts J, Lens L, Briels N, Carbone M)
Flanders Research Institute for Agriculture, Fisheries and Food, Belgium (Aerts J)
none at present