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  • The influence of (chronic) elevated levels of endogenous and exogenous glucocorticoids on the (re)activity of the Hypothalamic-Pituitary-Interrenal axis using carp (Cyprinus carpio) as a model: expression of key genes and UPLC-MS/MS quantification of a full glucocorticoid profile from egg to adult fish.

The influence of (chronic) elevated levels of endogenous and exogenous glucocorticoids on the (re)activity of the Hypothalamic-Pituitary-Interrenal axis using carp (Cyprinus carpio) as a model: expression of key genes and UPLC-MS/MS quantification of a full glucocorticoid profile from egg to adult fish.

StressChron Framework:

Project code 139
Acronym HPIONTO
Role Coordinator
Research area Unravelling the fundamentals of glucocorticoid actions across vertebrates
Research topic Glucocorticoid-mediated developmental programming and early life stress
Vertebrate Fish
Species Carp (Cyprinus carpio)

Abstract:

This study focuses on the influence of (chronic) elevated levels of endogenous and exogenous glucocorticoids on the (re)activity of the Hypothalamic-Pituitary-Interrenal axis using carp (Cyprinus carpio) as a model: expression of key genes and UPLC-MS/MS quantification of a full glucocorticoid profile from egg to adult fish.

Specifics:

Keywords: fish, ontogeny, HPI, glucocorticoid, stress

Funding: Stress Physiology Research Group

Status: On-going

Consortium:

Ghent University, Belgium (Aerts J, Pereira P)

Flanders Research Institute for Agriculture, Fisheries and Food, Belgium (Aerts J)

Output:

None at present

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