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1a-Hydroxycorticosterone in a shark tooth as biomarker for chronic stress in elasmobranchs

StressChron Framework:

Project code 153
Role Coordinator
Research area Unravelling the fundamentals of glucocorticoid actions across vertebrates
Research topic Mechanism(s) of glucocorticoid incorporation
Vertebrate Fish
Species shark (across species)


This study investigates chronic stress in sharks by quantification of 1α-hydroxycorticosterone using UPLC-MS/MS in a single shark tooth. Sharks continuously replace their teeth, making it a suitable non-invasive tissue. Depending on the species and life stage, tooth replacement rates can range from several days to several months, enabling us to quantify stress experienced by the animal in the preceding time period. The results of this project will serve in wildlife conservation, to evaluate the efficiency of marine protected areas for example, as in welfare evaluation of zoolife.


Keywords: fish, HPI, glucocorticoid, stress, tooth

Funding: Internal

Status: On-going


Ghent University, Belgium (Aerts J, Briels N)

Flanders Research Institute for Agriculture, Fisheries and Food, Belgium (Aerts J)


None at present

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