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  • Unravelling the effects of individual coping style and long-term glucocorticoid up-regulation on cardiac remodeling in Atlantic salmon (Salmo salar)

Unravelling the effects of individual coping style and long-term glucocorticoid up-regulation on cardiac remodeling in Atlantic salmon (Salmo salar)

Published on 21-06-2021 by Johan Aerts Projects

Putting a stop to salmon cardiac arrest in intensive aquaculture.

This project will advance significantly our understanding of the interplay between chronic stress, individual stress coping style on the pathogenesis of cardiac disease in salmonids. In addition, a potential strategy to mitigate cardiac remodeling will be tested. In all, it will provide innovative data pivotal for the development of more sustainable farming strategies by reducing cardiac morbidity and eventually pre-slaughter mortality in global salmon aquaculture.

The expected outcomes of this project include:

(i) significantly increasing our understanding of the generalizable effects of long-term elevation of GCs on the cardiac remodeling and performance of Atlantic salmon;

(ii) in-depth data on the interplay between stress coping style and the susceptibility of Atlantic salmon to cardiac diseases, leading to the possibility for early selection avoiding non-specific mortality at a later stage;

and (iii) elucidation of the modulating effects of exercise, by sustained swimming in raceways systems, on the level of GCs and its implication on the cardiac performance of Atlantic salmon.

Explore the mitigating potential of exercise for cardiac remodeling.

On-going StressChron project>>